Most Recent Publications
2024:
Proximity interactome of lymphatic VE-cadherin reveals mechanisms of junctional remodeling and reelin secretion. Serafin DS, Harris NR, Bálint L, Douglas ES, Caron KM. Nat Commun. 2024 Sep 4;15(1):7734. doi: 10.1038/s41467-024-51918-1. PMID: 39232006.
Meningeal lymphatic CGRP signaling governs pain via cerebrospinal fluid efflux and neuroinflammation in migraine models. Nelson-Maney NP, Bálint L, Beeson AL, Serafin DS, Kistner BM, Douglas ES, Siddiqui AH, Tauro AM, Caron KM. J Clin Invest. 2024 May 14;134(15):e175616. doi: 10.1172/JCI175616.
2023:
Clinical Potential of Adrenomedullin Signaling in the Cardiovascular System. Bálint L, Nelson-Maney NP, Tian Y, Serafin SD, Caron KM. Circ Res. 2023 Apr 28;132(9):1185-1202. doi: 10.1161/CIRCRESAHA.123.321673. Epub 2023 Apr 27.
Coumestrol induces oxidative stress and impairs migration and embryonic growth. Marbrey MW, Douglas ES, Goodwin ER, Caron KM. Reproduction. 2023 May 15;166(1):1-11. doi: 10.1530/REP-23-0017. Print 2023 Jul 1.
The ebb and flow of cardiac lymphatics: a tidal wave of new discoveries. Harris NR, Bálint L, Dy DM, Nielsen NR, Méndez HG, Aghajanian A, Caron KM. Physiol Rev. 2023 Jan 1;103(1):391-432. doi: 10.1152/physrev.00052.2021. Epub 2022 Aug 11.
2022:
Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development. Xu W, Nelson-Maney NP, Bálint L, Kwon HB, Davis RB, Dy DCM, Dunleavey JM, St Croix B, Caron KM. Int J Mol Sci. 2022 May 20;23(10):5712. doi: 10.3390/ijms23105712.
Dermal Lymphatic Capillaries Do Not Obey Murray’s Law. Talkington AM, Davis RB, Datto NC, Goodwin ER, Miller LA, Caron KM. Front Cardiovasc Med. 2022 Apr 12;9:840305. doi: 10.3389/fcvm.2022.840305.
Accelerated Development With Increased Bone Mass and Skeletal Response to Loading Suggest Receptor Activity Modifying Protein-3 as a Bone Anabolic Target. Pacharne S, Livesey M, Kadmiel M, Wang N, Caron KM, Richards GO, Skerry TM. Front Endocrinol (Lausanne). 2022 Jan 12;12:807882. doi: 10.3389/fendo.2021.807882.
VE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling. Harris NR, Nielsen NR, Pawlak JB, Aghajanian A, Rangarajan K, Serafin DS, Farber G, Dy DM, Nelson-Maney NP, Xu W, Ratra D, Hurr SH, Qian L, Scallan JP, Caron KM. Circ Res. 2022 Jan 7;130(1):5-23. doi: 10.1161/CIRCRESAHA.121.318852. Epub 2021 Nov 18.
2021:
Lymphatic Vasculature: An Emerging Therapeutic Target and Drug Delivery Route. Xu, W, Harris, NR, Caron, KM. Annual Reveiw of Medicine. 2021 Jan 27;72:167-182. doi: 10.1146/annurev-med-051419-114417.
Nociceptive nerves regulate haematopoietic stem cell mobilization. Gao X, Zhang D, Xu C, Li H, Caron KM, Frenette PS. Nature. 2021 Jan;589(7843):591-596. doi: 10.1038/s41586-020-03057-y.
2020:
The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. Kwon HB, Mackie DI, Bonnavion R, Mercier AL, Helker CSM, Son T, Guenter S, Serafin DS, Kim KW, Offermanns S, Caron KM, Stainier DYR. ACS Pharmacol Transl Sci. 2020 Jun 24;3(4):676-689. doi: 10.1021/acsptsci.0c00020. eCollection 2020 Aug 14.
Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface. Quinn KE, Matson BC, Caron KM. Placenta. 2020 Jun;95:18-25. doi: 10.1016/j.placenta.2020.04.007. Epub 2020 Apr 22.
A murine model of increased coronary sinus pressure induces myocardial edema with cardiac lymphatic dilation and fibrosis. Nielsen NR, Rangarajan KV, Mao L, Rockman HA, Caron KM. Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H895-H907. doi: 10.1152/ajpheart.00436.2019
Dawn of a New RAMPage. Serafin DS, Harris NR, Nielsen NR, Mackie DI, Caron KM. Trends Pharmacol Sci. 2020 Apr;41(4):249-265. doi: 10.1016/j.tips.2020.01.009.
Lymphatic Programing and Specialization in Hybrid Vessels. Pawlak JB, Caron KM. Front Physiol. 2020 Feb 20;11:114. doi: 10.3389/fphys.2020.00114.
Pinopodes: Recent advancements, current perspectives, and future directions. Quinn KE, Matson BC, Wetendorf M, Caron KM. Mol Cell Endocrinol. 2020 Feb 5;501:110644. doi: 10.1016/j.mce.2019.110644.